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Frequently Asked Questions About Hydrogen-Rich Water

If you have never tried molecular hydrogen supplements before or are interested in what sets our H2 tablets apart from other supplements on the market, check out our list of frequently asked questions! We will help you discover what hydrogen-rich water is, the benefit of consuming it daily, and best practices for taking our supplements.

Still Curious About Our H2 Tablets? Contact Us Today!

If you have reviewed these common questions and answers and still have a question, contact Drink HRW today! We are willing to answer any questions you may have about our products including H2 Beauty tablets, Rejuvenation H2 tablets, and AGEless Defense.


There are over 1500 publications on molecular hydrogen as a therapeutic agent, including 85 published human trials demonstrating a potential benefit in 170 different models across every organ, since the seminal publication in Nature Medicine, perhaps the most prestigious scientific journal.

Hydrogen dissolved or delivered via water, or “hydrogen water,” is the “go-to” route, with this systematic review of 321 publications citing it works at 100~ times less volume than H2 gas inhalation.

Check out our Discover Hydrogen page for more information.

There is limited evidence to suggest the best dosing protocols of molecular hydrogen, but we have found that a minimum of 1–2 tablets per day is required. Read our blog on hydrogen water dosing and protocols for more information.

Rejuvenation tablets react and disintegrate best in room temperature water with up to 200ppm of total dissolved solids. If you are using chilled water, or mineral water with high alkalinity, some residue may be present. It is still safe to drink. However, we always recommend using water sources within the specs the tablets were designed for.

This is a simple question with a complicated answer. First off, we are firmly of the position, backed by the overwhelming body of scientific literature, that whether a substance is synthetic or natural plays no role in either its toxicity or therapeutic properties. That said, we are asked this question frequently.

One way to look at it is to ask if anything like hydrogen tablets exist in nature, and the answer is no. The other way is to break down the active constituents in what will be consumed.

Molecular hydrogen is produced endogenously (within our bodies) in large amounts every day and is present within our cells. Further, there is documentation that the oldest water we have ever discovered, estimated at 2 billion years old, was “rich” in dissolved hydrogen gas, and 17 samples of water from the oldest rock we have on the planet also turned up hydrogen gas dissolved in the water. Additionally, one scientific theory that holds weight discusses the possibility that mitochondria evolved from H2-dependent single-cell organisms. Therefore, hydrogen gas has been with us since the very beginning.

As for the magnesium, while it is true that we do not naturally consume magnesium in its elemental form in our diet, the very reaction to create the molecular hydrogen converts the elemental magnesium to free magnesium ions, the precise form our bodies need.

As for the other active ingredients in the reaction, malic and tartaric acid, malic acid is derived from apples, and tartaric acid is derived from grapes.

There are additional excipients needed for manufacturing, such as dextrose as a binding agent, derived from a natural source and always present within our bodies (dextrose is glucose). The molecule of adipic acid, which is commercially produced in various methods, can be found naturally in beets and sugar cane.

We strive to obtain ingredients from sources that contain the least contaminants, from heavy metals to microbiological risks. Sometimes these ingredients come from a natural source, sometimes by a synthetic process. Regardless of process, the molecule is identical, with the contaminants being the key issue in regards to safety.

In the published literature there are no side effects from drinking hydrogen water that are directly attributed to molecular hydrogen, and it is believed to have a very high safety profile. Hydrogen is used to prevent decompression sickness at thousands of times higher concentrations. Note that these tablets do contain magnesium, so exceeding the recommended daily allowance of magnesium can have associated risks (i.e., diarrhea). We suggest limiting to no more than six tablets daily. In certain people with diabetes, H2 may exert a hypoglycemic effect, which can be normalized by patients lowering their insulin injection levels. So it is important to monitor glucose and insulin for diabetics.

The short answer is no. The longer explanation is this: Dextrose is present in the tablet as a binding agent, in a minuscule amount. It amounts for a fraction of a calorie and is not used as a sweetener.

No. The levels of magnesium in the Rejuvenation tablet are too low to be flammable, as is the level of hydrogen in the water created. Hydrogen has to exceed 4% of the atmospheric pressure to be explosive.

We have a comprehensive review comparing all technologies here:

Our hydrogen tablets deliver the highest concentration on the market, are clinically validated and the only legally marketed hydrogen water supplement* in the USA.
*other products may be legally marketed as foods or medical devices, although many are not. Other open cup tablets sold to various companies as private labels of our technology are also legally marketed.

While popular in some circles for claimed therapeutic benefits for specific ailments, food grade hydrogen peroxide [H2O2] is in no way similar to dissolved molecular hydrogen [H2] other than they both contain the word ‘hydrogen’. Hydrogen peroxide is a strong oxidizer and is used as a bleaching agent and disinfectant. Molecular hydrogen [H2] is a reducing agent/anti-oxidant.

Function In a Hydrogen Tablet, Other “natural” Options

“Natural” sweeteners such as stevia and monk fruit aren’t particularly water soluble, The sweetness of these alternatives is also slow building, so a much higher input is required. Due to the high input, and other challenges present in manufacturing, the cost increases substantially and the resuting end product diminishes dramatically in effectiveness. Our team does significant work in formulation, and while we have gotten both stevia and monk fruit ‘to work’, in a sense, it slows disintegration to ~5 minutes from ~75 seconds, and cuts the molecular hydrogen to 1/3 of retained levels that we observe in our currently marketed flavoured hydrogen tablet. That substantial of a drop in concentration and dosing of our hydrogen water was far too big a price for us. On top of this, the added costs, difficulty and overwhelmingly less positive taste tests were strong motivators, as well. As for other “natural sweeteners such as xylitol, for starters it is similar in sweetness to sugar and as such could not be used in the appropriate dosage to make a tablet. For that consideration alone, most options are not possible. As for sugar alcohols themselves, they tend to complex directly with the Magnesium during the reaction to make the H2, and as such do not have safety establishing them to be used, and are not suitable.

The Safety of Sucralose

From a scientific perspective there is no issues with sucralose, and in fact the safety is established to a substantially larger degree than most 'natural sweeteners' such as stevia and monk fruit. One of the big issues our company is battling against is 'chemophobia' and irrational fear mongering, which has become so prevalent in the 'natural industry' based on no sound science, perpetrated by those speaking outside their fields of expertise. As we say across our website 'safe and effective', regardless if a molecule is 'synthetic or natural'. While of course you can find publications decrying sucralose, this is true for all sweeteners. As science minded people we must asses the total body of evidence while looking for what has been replicated by numerous teams. We also must consider the dosing required.

Sucralose for instance has had safety established in dogs up to 900mg/Kg/day for 12 months ( ) and has been established by Canadian Diabetes Association to have no adverse events in taken at 9mg/Kg/day over a lifetime. For context, our hydrogen tablet has 10mg of sucralose, total. This means that daily lifetime safety with no toxicity or adverse events has been declared at an amount to take 65 tablets of ours a day for life, based on the sucralose in the hydrogen tablet and a ~150 pounds person

65 tablets a day would lead to hypermagnesia very quickly, with potentially serious adverse and even fatal affects

Additionally, this same 65 tablets a day would amount to a substantial amount of actual sugar (dextrose), which while insignificantly dosed in our tablet as a necessary binder (all tablets must have sugar), at 65 a day could contribute to increases in blood sugar leading to increased risk of many conditions

Here is an except from the FDA on sucraloses safety:

“Results from studies in the FDA approval process indicated a lack of risk associated with eating sucralose.[16][17][18][19] When the estimated daily intake (EDI) is compared to the intake at which adverse effects are seen (known as the "highest no-effects limit", or HNEL at 1500 mg/kg BW/day,[20] a large margin of safety exists. The bulk of sucralose ingested is not absorbed by the gastrointestinal tract (gut) and is directly excreted in the feces, while 11–27% of it is absorbed.[5] The amount absorbed from the gut is largely removed from the blood stream by the kidneys and eliminated in the urine, with 20–30% of the absorbed sucralose being metabolized.[5] This means that only between 2–8% of sucralose consumed is metabolized, on average.”

Remember, the dose makes the poison. Even water itself is toxic when enough is consumed.

As an alternative, the blue raspberry tablet is designed for taste. Our standard Rejuvenation hydrogen tablet contains no sucralose or flavours, and is more potent in delivering hydrogen water.


Hydrogen rich water is regular water that has been saturated with molecular hydrogen, or hydrogen gas (H2). Water, or H2O, is a chemical compound consisting of 2 hydrogen atoms (H) bonded with an oxygen atom (O). Hydrogen-rich water is a solution of H2 (molecular hydrogen) gas, that is simply dissolved in to H2O (water). Think of ‘carbonating’ water, used in sparkling waters and soda pops, but instead of using CO2 (carbon dioxide) gas, using H2 (molecular hydrogen) gas.

Some people enjoy adding lemon or lime juice to the water for taste. It may also slightly increase retention in an open cup, and will increase saturation in a sealed bottle.

The best way to prepare this is to prepare the water with the cap off for the beginning of the reaction. Wait until the tablet is roughly 80% reacted, and then seal the bottle and shake until it finishes. Take with you to go, waiting at least 5 minutes for the external pressure to saturate the H2 into the water and reach a new equilibrium.

The tablet has been refined and maximized to achieve the highest levels of H2 while being prepared in an open cup. See the 'how it works' and 'H2blue' sections for more details. The only reason to use a sealed bottle is if you want to take your H2 water to go.

While any type of water will work, with no difference between filtered, distilled, or tap, we recommend you do not use high pH water from an ionizer or other method. The reaction to create H2 relies on delicate chemistry, and using high pH water, such as '9.5' pH water from an ionizer, will reduce the amount of hydrogen created. For best results use water as close to 7 pH as possible.